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The molecular ion peak [M + H + ] observed at m / z 308.1 in electrospray ionisation mass spectrometry (ESI-MS) aligned with the expected mass

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47,59-62 Given that N 2 O can be used during spine surgery, this points to the necessity of routinely monitoring B 12 levels in patients with DCM to optimize surgical outcomes and prevent perioperative or postoperative neurological deficit development